EDR46505.1 protein (Dorea formicigenerans) - STRING interaction network

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EDR46505.1

Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (338 aa)

Predicted Functional Partners:

proS

0.818

mraW-2

0.566

EDR46506.1

0.524

truA-3

0.430

guaA

0.418

truA

0.416

Your Current Organism:

Dorea formicigenerans

NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDR46505.1	EDR46506.1	DORFOR_03117	DORFOR_03118	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	CAAX amino terminal protease family protein; COG: COG1266 Predicted metal-dependent membrane protease; Psort location: CytoplasmicMembrane, score: 9.99.	0.524
EDR46505.1	guaA	DORFOR_03117	DORFOR_01859	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.	0.418
EDR46505.1	mraW-2	DORFOR_03117	DORFOR_03116	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.	0.566
EDR46505.1	proS	DORFOR_03117	DORFOR_02892	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).	0.818
EDR46505.1	truA	DORFOR_03117	DORFOR_00232	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.416
EDR46505.1	truA-3	DORFOR_03117	DORFOR_03276	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.430
EDR46506.1	EDR46505.1	DORFOR_03118	DORFOR_03117	CAAX amino terminal protease family protein; COG: COG1266 Predicted metal-dependent membrane protease; Psort location: CytoplasmicMembrane, score: 9.99.	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.524
guaA	EDR46505.1	DORFOR_01859	DORFOR_03117	GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.418
guaA	proS	DORFOR_01859	DORFOR_02892	GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.	proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).	0.795
mraW-2	EDR46505.1	DORFOR_03116	DORFOR_03117	S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.566
mraW-2	truA	DORFOR_03116	DORFOR_00232	S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.464
mraW-2	truA-3	DORFOR_03116	DORFOR_03276	S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	0.464
proS	EDR46505.1	DORFOR_02892	DORFOR_03117	proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.818
proS	guaA	DORFOR_02892	DORFOR_01859	proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).	GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.	0.795
truA	EDR46505.1	DORFOR_00232	DORFOR_03117	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.416
truA	mraW-2	DORFOR_00232	DORFOR_03116	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.	0.464
truA-3	EDR46505.1	DORFOR_03276	DORFOR_03117	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	Dihydrouridine synthase (Dus); Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.	0.430
truA-3	mraW-2	DORFOR_03276	DORFOR_03116	tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.	S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.	0.464

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