STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pycPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1175 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; KEGG: tte:TTE1815 2.8e-136 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
    
 0.967
nifJ
KEGG: ctc:CTC01741 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
    
 0.955
EDR45865.1
Malic enzyme, NAD binding domain protein; KEGG: tte:TTE2332 3.2e-126 sfcA; malic enzyme K00027; COG: COG0281 Malic enzyme; Psort location: CytoplasmicMembrane, score: 9.76.
   
 0.951
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.945
EDR47140.1
KEGG: tte:TTE1208 1.4e-148 pycA; Pyruvate carboxylase, C-terminal domain/subunit K01960; COG: COG5016 Pyruvate/oxaloacetate carboxyltransferase; Psort location: Cytoplasmic, score: 8.87.
 
  
0.928
EDR47504.1
KEGG: lla:L67186 3.9e-137 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.927
EDR46411.1
KEGG: cno:NT01CX_0234 3.0e-132 citrate synthase I K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.927
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
    
 0.926
ppdK
Pyruvate, phosphate dikinase; KEGG: tte:TTE0981 0. ppsA2; Phosphoenolpyruvate synthase/pyruvate phosphate dikinase K01006; COG: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Psort location: Cytoplasmic, score: 9.98; Belongs to the PEP-utilizing enzyme family.
    
 0.925
EDR48334.1
Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-binding domain protein; KEGG: ctc:CTC02526 2.0e-126 porA; pyruvate synthase subunit porA K00169; COG: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit; Psort location: Cytoplasmic, score: 8.87.
     
 0.919
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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