Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDR45381.1RNA polymerase sigma factor, sigma-70 family; Psort location: Cytoplasmic, score: 8.87. (188 aa)    
Predicted Functional Partners:
EDR45391.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.744
EDR45389.1
Relaxase/mobilization nuclease domain protein; COG: COG3843 Type IV secretory pathway, VirD2 components (relaxase); Psort location: Cytoplasmic, score: 8.87.
  
     0.717
EDR45412.1
CHC2 zinc finger domain protein; KEGG: dde:Dde_2053 1.7e-10 DNA primase K02316; COG: NOG17367 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.701
EDR45411.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.695
EDR45395.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.692
EDR45376.1
Site-specific recombinase, phage integrase family; COG: COG0582 Integrase; Psort location: Cytoplasmic, score: 8.87; Belongs to the 'phage' integrase family.
 
    0.668
EDR45410.1
SNF2 family N-terminal domain protein; KEGG: chu:CHU_1468 5.2e-11 dpn; possible adenine-specific DNA methylase K00599; COG: COG4646 DNA methylase; Psort location: Extracellular, score: 7.50.
  
    0.659
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.655
EDR45377.1
Site-specific recombinase, phage integrase family; COG: COG0582 Integrase; Psort location: Cytoplasmic, score: 8.87; Belongs to the 'phage' integrase family.
 
    0.655
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.652
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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