Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDR45390.1Divergent AAA domain protein; KEGG: mma:MM0198 1.9e-28 ATP-dependent DNA helicase K01529; COG: COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen; Psort location: Cytoplasmic, score: 8.87. (470 aa)    
Predicted Functional Partners:
EDR48147.1
Hypothetical protein; KEGG: cgl:NCgl0024 3.8e-16 cgl0025; predicted transcriptional regulator K01529; COG: COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen; Psort location: Cytoplasmic, score: 8.87.
  
 
 
0.923
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
     
  0.900
EDR45389.1
Relaxase/mobilization nuclease domain protein; COG: COG3843 Type IV secretory pathway, VirD2 components (relaxase); Psort location: Cytoplasmic, score: 8.87.
 
    0.609
EDR45391.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.472
EDR46394.1
Hypothetical protein; KEGG: fnu:FN0191 3.2e-64 ATP-dependent DNA helicase RecG K01529; COG: COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen; Psort location: Cytoplasmic, score: 8.87.
  
     0.450
EDR46033.1
Hypothetical protein; COG: COG1373 Predicted ATPase (AAA+ superfamily); Psort location: Cytoplasmic, score: 8.87.
  
     0.422
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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