Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EDR45506.1Hypothetical protein; COG: NOG13188 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (411 aa)    
Predicted Functional Partners:
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
    
 0.833
EDR47568.1
KEGG: ctc:CTC00579 3.0e-107 sbcC; exonuclease sbcC K03546; COG: COG0419 ATPase involved in DNA repair; Psort location: Cytoplasmic, score: 9.98.
    
 0.759
EDR46261.1
Hypothetical protein; KEGG: cal:orf19.2417 2.5e-07 SMC5; structural maintenance of chromosomes protein K01553; COG: COG4717 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
    
 0.759
sbcD
Exonuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
   
 0.741
EDR46260.1
Hypothetical protein; KEGG: gox:GOX1019 1.6e-06 putative exonuclease K01146; COG: COG0420 DNA repair exonuclease; Psort location: Cytoplasmic, score: 8.87.
   
 0.741
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.728
EDR45507.1
Hypothetical protein; COG: COG1672 Predicted ATPase (AAA+ superfamily).
       0.645
EDR47485.1
Putative dGTPase; KEGG: cal:orf19.3100 1.3e-14 USO4; coiled-coil protein necessary for protein transport from ER to Golgi K01553; COG: COG4913 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
 
     0.608
EDR47484.1
Hypothetical protein; COG: NOG21901 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.543
EDR46203.1
Hypothetical protein; COG: KOG3704 Heparan sulfate D-glucosaminyl 3-O-sulfotransferase; Psort location: CytoplasmicMembrane, score: 7.63.
  
     0.511
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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