STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDR45512.1DNA-binding helix-turn-helix protein; KEGG: mmo:MMOB3450 0.00014 dam; adenine-specific DNA methyltransferase K06223; COG: NOG17530 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (100 aa)    
Predicted Functional Partners:
EDR45513.1
Toxin-antitoxin system, toxin component, RelE family; COG: COG4679 Phage-related protein; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.995
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.821
EDR45515.1
DNA-binding helix-turn-helix protein; KEGG: mmo:MMOB3450 0.0028 dam; adenine-specific DNA methyltransferase K06223; Psort location: Cytoplasmic, score: 8.87.
 
    
0.549
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.538
EDR45514.1
Hypothetical protein; COG: COG1943 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score: 8.87.
       0.493
EDR48434.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: btl:BALH_0703 2.0e-140 ndh; NADH dehydrogenase K00356; COG: COG0607 Rhodanese-related sulfurtransferase; Psort location: Cytoplasmic, score: 9.98.
   
 
  0.408
EDR45511.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.401
Your Current Organism:
Dorea formicigenerans
NCBI taxonomy Id: 411461
Other names: D. formicigenerans ATCC 27755, Dorea formicigenerans ATCC 27755
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.