STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflAPyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (255 aa)    
Predicted Functional Partners:
pflB
KEGG: bat:BAS0481 6.9e-259 formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
  
 0.991
EDM50979.1
Glycine radical domain protein; KEGG: lwe:lwe1422 5.0e-26 pflB; formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.65.
 
  
 0.987
fucO
Lactaldehyde reductase; KEGG: cpf:CPF_1046 1.6e-154 fucO; lactaldehyde reductase K00048; COG: COG1454 Alcohol dehydrogenase, class IV; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.569
EDM49929.1
KEGG: tma:TM0920 8.8e-53 alcohol dehydrogenase, iron-containing K00001; COG: COG1454 Alcohol dehydrogenase, class IV; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.569
EDM50978.1
Hypothetical protein; KEGG: pfa:PF11_0147 0.016 mitogen-activated protein kinase 2 K00870; COG: COG2607 Predicted ATPase (AAA+ superfamily); Psort location: Cytoplasmic, score: 8.87.
       0.559
EDM50982.1
KEGG: cno:NT01CX_1801 1.6e-14 noxC; nitroreductase family protein; COG: COG0778 Nitroreductase; Psort location: Cytoplasmic, score: 8.87.
       0.556
pyk
Pyruvate kinase; KEGG: tte:TTE1815 3.0e-141 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
     
 0.431
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
   
  
 0.409
Your Current Organism:
Eubacterium ventriosum
NCBI taxonomy Id: 411463
Other names: E. ventriosum ATCC 27560, Eubacterium ventriosum ATCC 27560
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