Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDM50539.1Divergent AAA domain protein; KEGG: cgl:NCgl0024 2.8e-16 cgl0025; predicted transcriptional regulator K01529; COG: COG2865 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen; Psort location: Cytoplasmic, score: 8.87. (425 aa)    
Predicted Functional Partners:
recG
Putative ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
   
 
  0.901
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.644
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.593
EDM50540.1
KEGG: ldb:Ldb0670 1.5e-25 phosphotyrosine protein phosphatase K01104; COG: COG0394 Protein-tyrosine-phosphatase; Psort location: Cytoplasmic, score: 8.87; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
       0.517
EDM50541.1
Oxidoreductase, aldo/keto reductase family protein; KEGG: mma:MM3156 6.8e-23 oxidoreductase; COG: COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases); Psort location: Cytoplasmic, score: 8.87.
       0.517
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.491
EDM49890.1
Hypothetical protein; KEGG: lmf:LMOf2365_2341 0.033 aminotransferase, class I K00842; COG: COG1373 Predicted ATPase (AAA+ superfamily).
  
     0.489
EDM51854.1
KEGG: cpf:CPF_2685 2.7e-51 rpoA; DNA-directed RNA polymerase, alpha subunit K03040; COG: COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit; Psort location: Cytoplasmic, score: 9.98.
    
   0.461
rpoA
KEGG: ljo:LJ0361 5.8e-33 DNA-directed RNA polymerase alpha chain K03040; COG: COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit; Psort location: Cytoplasmic, score: 9.98.
    
   0.461
EDM50666.1
KEGG: hpa:HPAG1_0089 1.3e-15 RNA polymerase sigma-80 factor K00960; COG: COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Psort location: Cytoplasmic, score: 9.65; Belongs to the sigma-70 factor family.
    
   0.449
Your Current Organism:
Eubacterium ventriosum
NCBI taxonomy Id: 411463
Other names: E. ventriosum ATCC 27560, Eubacterium ventriosum ATCC 27560
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.