STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
carAKEGG: ldb:Ldb1070 3.6e-111 carA2a; carbamoyl-phosphate synthase small chain K01954; COG: COG0505 Carbamoylphosphate synthase small subunit; Psort location: Cytoplasmic, score: 8.87; Belongs to the CarA family. (359 aa)    
Predicted Functional Partners:
pyrB
KEGG: cno:NT01CX_0395 2.0e-110 pyrB; aspartate carbamoyltransferase K00608; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.999
carB
KEGG: cpe:CPE2572 0. carB; carbamoyl-phosphate synthetase catalytic subunit K01955; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Psort location: Cytoplasmic, score: 8.87.
 0.999
pyrC
Amidohydrolase family protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
  
 0.997
argF
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
 
 
 0.966
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 
 0.963
pyrD
Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate.
 
  
 0.962
pyrI
Aspartate carbamoyltransferase regulatory chain, allosteric domain protein; KEGG: ctc:CTC02383 4.0e-34 aspartate carbamoyltransferase regulatory chain K00610; COG: COG1781 Aspartate carbamoyltransferase, regulatory subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.952
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
  
 0.952
pyrK
Oxidoreductase NAD-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
  
  
 0.947
glnA
KEGG: chy:CHY_0704 1.5e-151 glnA1; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score: 9.98.
  
 
 0.921
Your Current Organism:
Eubacterium ventriosum
NCBI taxonomy Id: 411463
Other names: E. ventriosum ATCC 27560, Eubacterium ventriosum ATCC 27560
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