STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas1CRISPR-associated endonuclease Cas1, DVULG subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (343 aa)    
Predicted Functional Partners:
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.999
cas4
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
 
 0.998
EDN01973.1
COG: COG3649 Uncharacterized protein predicted to be involved in DNA repair; Psort location: Cytoplasmic, score:8.96.
 
   
 0.963
cas5d
CRISPR-associated protein Cas5, Dvulg subtype; COG: NOG08906 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
 
     0.959
csd1
CRISPR-associated protein, Csd1 family; COG: NOG06096 non supervised orthologous group.
 
     0.954
EDN01969.1
Helicase C-terminal domain protein; KEGG: afu:AF0071 2.4e-07 ATP-dependent RNA helicase, putative; COG: COG1203 Predicted helicases; Psort location: Cytoplasmic, score:8.96.
 
  
 0.901
EDM98332.1
Reverse transcriptase (RNA-dependent DNA polymerase); KEGG: rha:RHA1_ro10191 5.0e-34 RNA-directed DNA polymerase K00986; COG: COG3344 Retron-type reverse transcriptase.
      0.870
EDM99305.1
CRISPR-associated endonuclease Cas3-HD; COG: COG1203 Predicted helicases.
 
  
 0.821
EDM99339.1
Putative integration host factor, beta subunit; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
    
   0.788
EDN01970.1
Hypothetical protein; Psort location: Cytoplasmic, score:8.96.
       0.701
Your Current Organism:
Pseudoflavonifractor capillosus
NCBI taxonomy Id: 411467
Other names: Bacteroides capillosus ATCC 29799, P. capillosus ATCC 29799, Pseudoflavonifractor capillosus ATCC 29799, Pseudoflavonifractor capillosus str. ATCC 29799, Pseudoflavonifractor capillosus strain ATCC 29799
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.