STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemBKEGG: cac:CAC0100 1.1e-102 hemB; porphobilinogen synthase K01698; COG: COG0113 Delta-aminolevulinic acid dehydratase; Psort location: Cytoplasmic, score:8.96; Belongs to the ALAD family. (328 aa)    
Predicted Functional Partners:
cobA
uroporphyrinogen-III C-methyltransferase; KEGG: dvu:DVU0734 4.7e-102 uroporphyrinogen III synthase/methyltransferase K02302:K01719; COG: COG1587 Uroporphyrinogen-III synthase; Psort location: Cytoplasmic, score:8.96.
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.998
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; KEGG: ecc:c0189 1.6e-133 hemL; glutamate-1-semialdehyde aminotransferase K01845; COG: COG0001 Glutamate-1-semialdehyde aminotransferase; Psort location: Cytoplasmic, score:8.96.
 
 
 0.997
EDN01170.1
Siroheme synthase domain protein; KEGG: pae:PA2611 1.3e-19 cysG; uroporphyrin-III C-methyltransferase / precorrin-2 oxidase / ferrochelatase K02302:K02303:K02304; COG: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); Psort location: Cytoplasmic, score:8.96.
 
 
 0.963
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.961
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
     
 0.702
cbiN
Cobalt transport protein; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import; Belongs to the CbiN family.
     
 0.699
cobI
KEGG: mst:Msp_0038 4.0e-34 cbiL; CbiL K03394; COG: COG2243 Precorrin-2 methylase; Psort location: Cytoplasmic, score:8.96; Belongs to the precorrin methyltransferase family.
     
 0.692
cobM
KEGG: mta:Moth_1092 3.6e-72 precorrin-4 C11-methyltransferase K03396; COG: COG2875 Precorrin-4 methylase.
 
   
 0.669
cbiQ
COG: COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters.
     
 0.663
Your Current Organism:
Pseudoflavonifractor capillosus
NCBI taxonomy Id: 411467
Other names: Bacteroides capillosus ATCC 29799, P. capillosus ATCC 29799, Pseudoflavonifractor capillosus ATCC 29799, Pseudoflavonifractor capillosus str. ATCC 29799, Pseudoflavonifractor capillosus strain ATCC 29799
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