sigK protein (Clostridium scindens) - STRING interaction network

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sigK

RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (208 aa)

Predicted Functional Partners:

spo0A_1

0.817

spo0A_4

0.817

spo0A_2

0.817

spo0A

0.809

spoIIAB

0.800

SpoIIAA

0.788

spoIVB

0.773

spoIVA

0.773

spoVAE

0.772

spoVAD

0.772

Your Current Organism:

Clostridium scindens

NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SpoIIAA	sigK	CLOSCI_02268	CLOSCI_00041	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	0.788
SpoIIAA	spo0A	CLOSCI_02268	CLOSCI_00435	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	0.799
SpoIIAA	spo0A_1	CLOSCI_02268	CLOSCI_01956	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	Sporulation initiation factor Spo0A domain protein; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.	0.800
SpoIIAA	spo0A_2	CLOSCI_02268	CLOSCI_03058	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	Sporulation initiation factor Spo0A domain protein; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.	0.799
SpoIIAA	spo0A_4	CLOSCI_02268	CLOSCI_02419	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	Sporulation initiation factor Spo0A domain protein; COG: COG0784 FOG: CheY-like receiver.	0.807
SpoIIAA	spoIIAB	CLOSCI_02268	CLOSCI_02267	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.998
SpoIIAA	spoIVA	CLOSCI_02268	CLOSCI_00690	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	Stage IV sporulation protein A; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.	0.837
SpoIIAA	spoIVB	CLOSCI_02268	CLOSCI_00434	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	SpoIVB peptidase; KEGG: btl:BALH_3781 9.1e-51 spoIVB; stage IV sporulation protein B; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1.	0.767
SpoIIAA	spoVAD	CLOSCI_02268	CLOSCI_02261	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	Stage V sporulation protein AD; COG: NOG06312 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.75.	0.923
SpoIIAA	spoVAE	CLOSCI_02268	CLOSCI_02260	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	Stage V sporulation protein AE; COG: NOG13202 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.	0.920
sigK	SpoIIAA	CLOSCI_00041	CLOSCI_02268	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	KEGG: ava:Ava_0744 4.9e-05 anti-sigma-factor antagonist (STAS) and sugar transfersase K00996; COG: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); Psort location: Cytoplasmic, score: 8.87.	0.788
sigK	spo0A	CLOSCI_00041	CLOSCI_00435	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.	0.809
sigK	spo0A_1	CLOSCI_00041	CLOSCI_01956	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Sporulation initiation factor Spo0A domain protein; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.	0.817
sigK	spo0A_2	CLOSCI_00041	CLOSCI_03058	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Sporulation initiation factor Spo0A domain protein; COG: COG0784 FOG: CheY-like receiver; Psort location: Cytoplasmic, score: 8.87.	0.817
sigK	spo0A_4	CLOSCI_00041	CLOSCI_02419	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Sporulation initiation factor Spo0A domain protein; COG: COG0784 FOG: CheY-like receiver.	0.817
sigK	spoIIAB	CLOSCI_00041	CLOSCI_02267	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Anti-sigma F factor; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.	0.800
sigK	spoIVA	CLOSCI_00041	CLOSCI_00690	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage IV sporulation protein A; COG: NOG05962 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.	0.773
sigK	spoIVB	CLOSCI_00041	CLOSCI_00434	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	SpoIVB peptidase; KEGG: btl:BALH_3781 9.1e-51 spoIVB; stage IV sporulation protein B; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1.	0.773
sigK	spoVAD	CLOSCI_00041	CLOSCI_02261	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage V sporulation protein AD; COG: NOG06312 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.75.	0.772
sigK	spoVAE	CLOSCI_00041	CLOSCI_02260	RNA polymerase sigma-K factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.	Stage V sporulation protein AE; COG: NOG13202 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.26.	0.772

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