Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ComMMg chelatase-like protein; KEGG: chu:CHU_0354 4.5e-120 ch1I; magnesium chelatase, subunit ChlI K07391; COG: COG0606 Predicted ATPase with chaperone activity; Psort location: Cytoplasmic, score: 8.87. (513 aa)    
Predicted Functional Partners:
dprA
DNA protecting protein DprA; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; Psort location: Cytoplasmic, score: 8.87.
 
 0.969
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.846
EDS07521.1
TIGR00252 family protein; KEGG: sat:SYN_00772 3.0e-20 endonuclease; COG: COG0792 Predicted endonuclease distantly related to archaeal Holliday junction resolvase; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0102 family.
 
  
 0.751
EDS06437.1
comF family protein; KEGG: reh:H16_A0339 2.1e-21 predicted amidophosphoribosyltransferase; COG: COG1040 Predicted amidophosphoribosyltransferases; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.742
codY
GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family.
       0.698
EDS08725.1
Tetratricopeptide repeat protein; KEGG: eci:UTI89_C2868 4.7e-27 yphG; hypothetical protein YphG K00754; COG: NOG06209 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.513
comEC_1
DNA internalization competence protein ComEC/Rec2-like protein; COG: COG0658 Predicted membrane metal-binding protein; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.508
EDS08724.1
Hypothetical protein.
       0.496
recJ
KEGG: cac:CAC2232 4.3e-147 recJ; SsDNA exonuclease, RecJ K07462; COG: COG0608 Single-stranded DNA-specific exonuclease; Psort location: Cytoplasmic, score: 8.87.
 
     0.477
EDS08730.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.456
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.