| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS08176.1 | aroE | CLOSCI_00487 | CLOSCI_00694 | RNA-binding protein, YhbY family; COG: COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein. | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.560 |
| EDS08176.1 | rny_1 | CLOSCI_00487 | CLOSCI_00489 | RNA-binding protein, YhbY family; COG: COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein. | Hydrolase, HD family; KEGG: tde:TDE1747 8.4e-22 nadD; nicotinate (nicotinamide) nucleotide adenylyltransferase K00969; COG: COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism; Psort location: Cytoplasmic, score: 8.87. | 0.855 |
| EDS08176.1 | yqeG | CLOSCI_00487 | CLOSCI_00058 | RNA-binding protein, YhbY family; COG: COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein. | HAD phosphatase, family IIIA; KEGG: saa:SAUSA300_1557 2.5e-23 hydrolase, HAD-superfamily, subfamily IIIA K01112; COG: COG2179 Predicted hydrolase of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | 0.449 |
| aroE | EDS08176.1 | CLOSCI_00694 | CLOSCI_00487 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | RNA-binding protein, YhbY family; COG: COG1534 Predicted RNA-binding protein containing KH domain, possibly ribosomal protein. | 0.560 |
| aroE | aroK | CLOSCI_00694 | CLOSCI_00057 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.994 |
| aroE | gltC_5 | CLOSCI_00694 | CLOSCI_00056 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 1.6e-21 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family. | 0.467 |
| aroE | rny_1 | CLOSCI_00694 | CLOSCI_00489 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Hydrolase, HD family; KEGG: tde:TDE1747 8.4e-22 nadD; nicotinate (nicotinamide) nucleotide adenylyltransferase K00969; COG: COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism; Psort location: Cytoplasmic, score: 8.87. | 0.583 |
| aroE | ylqF | CLOSCI_00694 | CLOSCI_01327 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.578 |
| aroE | yqeG | CLOSCI_00694 | CLOSCI_00058 | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | HAD phosphatase, family IIIA; KEGG: saa:SAUSA300_1557 2.5e-23 hydrolase, HAD-superfamily, subfamily IIIA K01112; COG: COG2179 Predicted hydrolase of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | 0.585 |
| aroK | aroE | CLOSCI_00057 | CLOSCI_00694 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.994 |
| aroK | efp | CLOSCI_00057 | CLOSCI_00059 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.858 |
| aroK | gltC_5 | CLOSCI_00057 | CLOSCI_00056 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 1.6e-21 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family. | 0.488 |
| aroK | yqeG | CLOSCI_00057 | CLOSCI_00058 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | HAD phosphatase, family IIIA; KEGG: saa:SAUSA300_1557 2.5e-23 hydrolase, HAD-superfamily, subfamily IIIA K01112; COG: COG2179 Predicted hydrolase of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | 0.804 |
| cdaR | mecB | CLOSCI_04050 | CLOSCI_02646 | Hypothetical protein; KEGG: shn:Shewana3_2682 0.00084 transcriptional regulator, CdaR K01694; COG: COG3835 Sugar diacid utilization regulator; Psort location: Cytoplasmic, score: 8.87. | COG: COG4862 Negative regulator of genetic competence, sporulation and motility; Psort location: Cytoplasmic, score: 8.87. | 0.712 |
| cdaR | yqeG | CLOSCI_04050 | CLOSCI_00058 | Hypothetical protein; KEGG: shn:Shewana3_2682 0.00084 transcriptional regulator, CdaR K01694; COG: COG3835 Sugar diacid utilization regulator; Psort location: Cytoplasmic, score: 8.87. | HAD phosphatase, family IIIA; KEGG: saa:SAUSA300_1557 2.5e-23 hydrolase, HAD-superfamily, subfamily IIIA K01112; COG: COG2179 Predicted hydrolase of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | 0.401 |
| efp | aroK | CLOSCI_00059 | CLOSCI_00057 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.858 |
| efp | yqeG | CLOSCI_00059 | CLOSCI_00058 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | HAD phosphatase, family IIIA; KEGG: saa:SAUSA300_1557 2.5e-23 hydrolase, HAD-superfamily, subfamily IIIA K01112; COG: COG2179 Predicted hydrolase of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | 0.668 |
| gltC_5 | aroE | CLOSCI_00056 | CLOSCI_00694 | LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 1.6e-21 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family. | Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.467 |
| gltC_5 | aroK | CLOSCI_00056 | CLOSCI_00057 | LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 1.6e-21 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.488 |
| gltC_5 | yqeG | CLOSCI_00056 | CLOSCI_00058 | LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 1.6e-21 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family. | HAD phosphatase, family IIIA; KEGG: saa:SAUSA300_1557 2.5e-23 hydrolase, HAD-superfamily, subfamily IIIA K01112; COG: COG2179 Predicted hydrolase of the HAD superfamily; Psort location: Cytoplasmic, score: 8.87. | 0.488 |