Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS08693.1Hypothetical protein; KEGG: ava:Ava_3862 0.00024 regulatory protein, MerR; COG: COG4978 Transcriptional regulator, effector-binding domain/component. (52 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.847
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.814
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
   0.813
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.812
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.761
sigF
Putative RNA polymerase sigma-F factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.761
rpoD-2
Hypothetical protein; KEGG: reh:H16_A1626 3.9e-06 rpoD1; DNA-directed RNA polymerase sigma subunit (RpoD) K00960; COG: COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Psort location: Cytoplasmic, score: 9.98.
  
 
 0.761
EDS06111.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.761
EDS08694.1
ABC-2 type transporter; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
 
    0.759
drrA_2
KEGG: fal:FRAAL2549 1.2e-34 antibiotic resistance ATP-binding protein K06020; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
     0.636
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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