Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
nylBBeta-lactamase; KEGG: mma:MM3157 3.4e-35 putative 6-aminohexanoate-dimer hydrolase; COG: COG1680 Beta-lactamase class C and other penicillin binding proteins; Psort location: Cytoplasmic, score: 8.87. (323 aa)    
Predicted Functional Partners:
hmrR
Transcriptional regulator, MerR family; KEGG: eci:UTI89_C3737 2.5e-06 yhdM; Zn(II)-responsive regulator of ZntA; COG: COG4978 Transcriptional regulator, effector-binding domain/component; Psort location: Cytoplasmic, score: 8.87.
 
    0.884
zntR_1
Transcriptional regulator, MerR family; KEGG: eci:UTI89_C3737 3.2e-07 yhdM; Zn(II)-responsive regulator of ZntA; COG: NOG23448 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
 
     0.663
EDS05309.1
Hypothetical protein; COG: COG2207 AraC-type DNA-binding domain-containing proteins; Psort location: Cytoplasmic, score: 8.87.
 
     0.555
EDS08694.1
ABC-2 type transporter; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
 
   
 0.534
SrfAA
AMP-binding enzyme; KEGG: ava:Ava_1613 5.8e-204 non-ribosomal peptide synthase K00644; COG: COG1020 Non-ribosomal peptide synthetase modules and related proteins; Psort location: Cytoplasmic, score: 9.96; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.527
drrA_2
KEGG: fal:FRAAL2549 1.2e-34 antibiotic resistance ATP-binding protein K06020; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
     0.503
EDS08693.1
Hypothetical protein; KEGG: ava:Ava_3862 0.00024 regulatory protein, MerR; COG: COG4978 Transcriptional regulator, effector-binding domain/component.
 
     0.420
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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