Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
EDS08494.1Helicase C-terminal domain protein; KEGG: mbo:Mb2127 1.1e-13 helZ; probable helicase HelZ; COG: COG0553 Superfamily II DNA/RNA helicases, SNF2 family; Psort location: Cytoplasmic, score: 8.87. (470 aa)    
Predicted Functional Partners:
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
 0.913
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.906
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 0.904
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.899
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.872
EDS06380.1
DNA primase small subunit; KEGG: ddi:DDB0214830 0.00013 repB; transcription factor IIH subunit K01529; COG: COG4951 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.827
EDS08492.1
Hypothetical protein; COG: COG1475 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87.
       0.786
EDS08493.1
Hypothetical protein; KEGG: eci:UTI89_C2238 5.7e-74 ibrA; hypothetical protein YbdN K00390; COG: COG3969 Predicted phosphoadenosine phosphosulfate sulfotransferase; Psort location: Cytoplasmic, score: 8.87.
       0.786
recQ
KEGG: cpf:CPF_0327 4.3e-140 recQ; ATP-dependent DNA helicase RecQ K03654; COG: COG0514 Superfamily II DNA helicase; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.779
EDS08495.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.773
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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