Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
sigM_1Sigma-70 region 2; KEGG: shn:Shewana3_0763 5.0e-11 RNA polymerase, sigma-24 subunit, ECF subfamily K00058; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. ECF subfamily. (158 aa)    
Predicted Functional Partners:
EDS08563.1
Hypothetical protein; COG: COG5660 Predicted integral membrane protein; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.944
SigR
Sigma-70 region 2; KEGG: bcz:BCZK3297 3.7e-15 RNA polymerase ECF-type sigma factor K03088; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.693
SigW_2
Sigma-70 region 2; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.646
sigW_1
Sigma-70 region 2; KEGG: reh:H16_A2563 7.3e-10 rpoE1; DNA-directed RNA polymerase sigma subunit (RpoE,sigma24) K00960; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.570
sigM_2
Sigma-70 region 2; KEGG: btl:BALH_3229 2.0e-14 sigW; RNA polymerase sigma-70 factor, ECF subfamily K00960; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog.
  
     0.565
kamA
KamA family protein; KEGG: dde:Dde_2747 3.1e-66 putative lysine 2,3-aminomutase K01843; COG: COG1509 Lysine 2,3-aminomutase; Psort location: Cytoplasmic, score: 8.87.
   
   0.523
trxA
Thioredoxin; KEGG: mbo:Mb3945 4.5e-26 trxC; thioredoxin TrxC (TRX) (MPT46) K03671; COG: COG0526 Thiol-disulfide isomerase and thioredoxins; Psort location: Cytoplasmic, score: 9.98; Belongs to the thioredoxin family.
     
 0.503
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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