Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDS08578.1Hypothetical protein. (76 aa)    
Predicted Functional Partners:
pfp_2
Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
       0.718
EDS08580.1
Hypothetical protein; KEGG: ehi:285.t00008 1.0e-17 NAD(FAD)-dependent dehydrogenase, putative K00111; COG: COG3862 Uncharacterized protein with conserved CXXC pairs; Psort location: Cytoplasmic, score: 8.87.
       0.520
trxB_3
Pyridine nucleotide-disulfide oxidoreductase; KEGG: ctc:CTC02435 5.1e-121 sarcosine oxidase alpha subunit K00301; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 8.87.
       0.516
lhgO
FAD dependent oxidoreductase; KEGG: ctc:CTC02436 1.9e-128 glycerol-3-phosphate dehydrogenase K00111; COG: COG0579 Predicted dehydrogenase; Psort location: Cytoplasmic, score: 8.87.
       0.503
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
       0.503
EDS08576.1
Hypothetical protein; KEGG: cpf:CPF_1123 1.3e-16 cell wall-associated serine proteinase K01361; COG: NOG17334 non supervised orthologous group.
       0.436
EDS08577.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.436
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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