Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IscR_2Transcriptional regulator, Rrf2 family; KEGG: ama:AM656 1.2e-08 aminotransferase, class V K04487; COG: COG1959 Predicted transcriptional regulator; Psort location: Cytoplasmic, score: 8.87. (166 aa)    
Predicted Functional Partners:
cymR_1
Transcriptional regulator, Rrf2 family; KEGG: ama:AM656 3.4e-09 aminotransferase, class V K04487; COG: COG1959 Predicted transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
 
    
0.760
nifS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
  
 0.676
iscS_2
Aminotransferase, class V; KEGG: tte:TTE1663 8.8e-101 nifS; Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes K04487; COG: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.650
nifU
Fe-S iron-sulfur cluster assembly protein, NifU family; KEGG: rxy:Rxyl_1354 1.2e-21 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase K00566; COG: COG0822 NifU homolog involved in Fe-S cluster formation; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.576
mgl_1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: bth:BT2387 1.2e-167 O-acetylhomoserine (thiol)-lyase K01740; COG: COG2873 O-acetylhomoserine sulfhydrylase; Psort location: Cytoplasmic, score: 9.98.
       0.573
sufS_2
Cysteine desulfurase family protein; KEGG: tde:TDE2460 1.5e-87 aminotransferase, class V; COG: COG0520 Selenocysteine lyase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.566
cysK
Cysteine synthase A; KEGG: chy:CHY_0808 2.3e-102 cysK; cysteine synthase A K01738; COG: COG0031 Cysteine synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
  
 0.532
CspA
Cold-shock DNA-binding domain protein; COG: COG1278 Cold shock proteins; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.470
EDS08353.1
Hypothetical protein; COG: COG0822 NifU homolog involved in Fe-S cluster formation; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.421
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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