Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
mprFHypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. (351 aa)    
Predicted Functional Partners:
UgtP
Monogalactosyldiacylglycerol synthase, C-terminal domain protein; KEGG: btl:BALH_0448 1.0e-33 ugtP; 1,2-diacylglycerol 3-glucosyltransferase K03429; COG: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.839
pdaA_1
Polysaccharide deacetylase; KEGG: bha:BH1917 8.4e-25 notB; chitooligosaccharide deacetylase K01463; COG: COG0726 Predicted xylanase/chitin deacetylase; Psort location: Cytoplasmic, score: 9.65.
  
  
 0.787
deoD_1
Phosphorylase family; KEGG: fal:FRAAL4002 2.1e-37 putative purine-nucleoside phosphorylase; COG: NOG30060 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.589
YfiR
Transcriptional regulator, TetR family; COG: COG1309 Transcriptional regulator; Psort location: Cytoplasmic, score: 8.87.
       0.584
EDS08058.1
Hypothetical protein; COG: NOG34170 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.570
EDS08065.1
Hypothetical protein.
       0.493
EDS05139.1
Hypothetical protein.
 
   
 0.414
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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