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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypBHydrogenase accessory protein HypB; KEGG: tte:TTE2387 0.00013 argK; putative periplasmic protein kinase ArgK and related GTPases of G3E family K07588; COG: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; Psort location: Cytoplasmic, score: 9.98. (222 aa)    
Predicted Functional Partners:
hypA_2
Putative hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.968
hypA_1
Hydrogenase expression/synthesis hypA family; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.920
gltD_1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: tma:TM1217 1.5e-71 glutamate synthase (NADPH) small chain K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 9.98.
 
  
 0.915
EDS08070.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.838
EDS06174.1
4Fe-4S binding domain protein; KEGG: mma:MM1824 0.00011 formylmethanofuran dehydrogenase K00205; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.820
HydA_1
PAS domain S-box protein; KEGG: cno:NT01CX_0464 1.5e-44 Fe-hydrogenase large subunit family protein K00532; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87.
  
    0.785
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.610
EDS08074.1
Hypothetical protein.
       0.559
thiL
Hypothetical protein; KEGG: mth:MTH1374 9.2e-06 phosphoribosylformylglycinamidine synthase II K01952; COG: COG0309 Hydrogenase maturation factor; Psort location: CytoplasmicMembrane, score: 7.80.
  
  
 0.532
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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