Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
larCTIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family. (408 aa)    
Predicted Functional Partners:
nadE_1
TIGR00268 family protein; KEGG: sat:SYN_00475 1.1e-43 GMP synthase (glutamine-hydrolyzing) K01951; COG: COG1606 ATP-utilizing enzymes of the PP-loop superfamily; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.876
purE_3
Hypothetical protein; KEGG: sat:SYN_00474 5.8e-65 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K01587; COG: COG1691 NCAIR mutase (PurE)-related proteins; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.872
EDS06103.1
Hypothetical protein; KEGG: sat:SYN_00474 9.1e-35 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K01587; COG: COG1691 NCAIR mutase (PurE)-related proteins; Psort location: Cytoplasmic, score: 8.87.
 
  
 0.872
EDS06107.1
Hypothetical protein; KEGG: sat:SYN_00474 1.4e-20 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit K01587; COG: COG1691 NCAIR mutase (PurE)-related proteins.
 
  
 0.872
EDS06102.1
Hypothetical protein; KEGG: sat:SYN_00475 3.0e-08 GMP synthase (glutamine-hydrolyzing) K01951; COG: COG1606 ATP-utilizing enzymes of the PP-loop superfamily.
  
 0.869
EDS08076.1
Transposase-like protein; COG: COG1943 Transposase and inactivated derivatives.
       0.479
cbiM
Cobalamin biosynthesis protein CbiM; Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import.
  
    0.441
TilS_2
Hypothetical protein; KEGG: sat:SYN_00475 1.3e-06 GMP synthase (glutamine-hydrolyzing) K01951; COG: COG1606 ATP-utilizing enzymes of the PP-loop superfamily.
  
  
 0.403
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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