Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS08076.1Transposase-like protein; COG: COG1943 Transposase and inactivated derivatives. (142 aa)    
Predicted Functional Partners:
EDS08077.1
Hypothetical protein.
       0.561
SigR
Sigma-70 region 2; KEGG: bcz:BCZK3297 3.7e-15 RNA polymerase ECF-type sigma factor K03088; COG: COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog; Psort location: Cytoplasmic, score: 8.87; Belongs to the sigma-70 factor family. ECF subfamily.
       0.550
EDS08079.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.550
larC
TIGR00299 family protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
       0.479
EDS08080.1
Haloacid dehalogenase-like hydrolase; KEGG: smu:SMU.1254 7.6e-63 conserved hypothetical protein K01091; COG: COG0546 Predicted phosphatases; Psort location: Cytoplasmic, score: 8.87.
       0.410
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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