Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
phoU_2Na/Pi-cotransporter II-like protein; COG: COG1283 Na+/phosphate symporter; Psort location: CytoplasmicMembrane, score: 9.97. (549 aa)    
Predicted Functional Partners:
ribF
Riboflavin biosynthesis protein RibF; KEGG: vpa:VP0533 3.7e-47 riboflavin kinase/FMN adenylyltransferase K00861:K00953; COG: COG0196 FAD synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the ribF family.
       0.753
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.704
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
       0.678
NrnA
DHHA1 domain protein; KEGG: tma:TM0715 4.6e-11 tRNA nucleotidyltransferase (CCA-adding enzyme) K00974; COG: COG0618 Exopolyphosphatase-related proteins; Psort location: Cytoplasmic, score: 8.87.
       0.669
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
       0.563
EDS08093.1
Hypothetical protein; COG: COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination; Psort location: Cytoplasmic, score: 8.87.
       0.540
rplGA
COG: COG1358 Ribosomal protein HS6-type (S12/L30/L7a); Psort location: Cytoplasmic, score: 8.87.
       0.539
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
       0.497
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
       0.474
rimP
Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
       0.448
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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