close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phoU_2Na/Pi-cotransporter II-like protein; COG: COG1283 Na+/phosphate symporter; Psort location: CytoplasmicMembrane, score: 9.97. (549 aa)    
Predicted Functional Partners:
ribF
Riboflavin biosynthesis protein RibF; KEGG: vpa:VP0533 3.7e-47 riboflavin kinase/FMN adenylyltransferase K00861:K00953; COG: COG0196 FAD synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the ribF family.
       0.753
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.703
rbfA
Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.
       0.675
NrnA
DHHA1 domain protein; KEGG: tma:TM0715 4.6e-11 tRNA nucleotidyltransferase (CCA-adding enzyme) K00974; COG: COG0618 Exopolyphosphatase-related proteins; Psort location: Cytoplasmic, score: 8.87.
       0.670
infB
Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
       0.563
EDS08093.1
Hypothetical protein; COG: COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination; Psort location: Cytoplasmic, score: 8.87.
       0.539
rplGA
COG: COG1358 Ribosomal protein HS6-type (S12/L30/L7a); Psort location: Cytoplasmic, score: 8.87.
       0.537
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
       0.497
nusA
Transcription termination factor NusA; Participates in both transcription termination and antitermination.
       0.476
rimP
Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
       0.445
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.