Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
argRArginine repressor; Regulates arginine biosynthesis genes. (149 aa)    
Predicted Functional Partners:
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
  
  
 0.921
argJ
Glutamate N-acetyltransferase/amino-acid acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family.
  
  
 0.920
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
  
 0.875
argG
KEGG: chy:CHY_2260 4.7e-134 argG; argininosuccinate synthase K01940; COG: COG0137 Argininosuccinate synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.871
nadK
NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
  
 0.863
rrmJ
KEGG: cff:CFF8240_1111 1.0e-26 rrmJ; ribosomal RNA large subunit methyltransferase J K00599; COG: COG1189 Predicted rRNA methylase; Psort location: Cytoplasmic, score: 8.87.
  
    0.858
dxs
1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily.
  
    0.832
EDS08113.1
COG: COG1302 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
 
     0.829
argH
Argininosuccinate lyase; KEGG: cpe:CPE0690 2.3e-139 argH; argininosuccinate lyase K01755; COG: COG0165 Argininosuccinate lyase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.829
EDS08117.1
Polyprenyl synthetase; KEGG: gvi:gll0416 1.7e-58 crtE; geranylgeranyl pyrophosphate synthase K00804; COG: COG0142 Geranylgeranyl pyrophosphate synthase; Psort location: Cytoplasmic, score: 9.98; Belongs to the FPP/GGPP synthase family.
     
 0.819
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.