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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
isfDKEGG: nwi:Nwi_0477 2.7e-35 short-chain dehydrogenase/reductase SDR; COG: COG0300 Short-chain dehydrogenases of various substrate specificities; Psort location: Cytoplasmic, score: 9.98; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)    
Predicted Functional Partners:
RsmF
NOL1/NOP2/sun family protein; KEGG: lsl:LSL_0999 8.9e-76 putative 23S rRNA m(5)C methyltransferase K00599; COG: COG3270 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87.
       0.808
RsuA
Pseudouridylate synthase; KEGG: tte:TTE0052 3.6e-63 rsuA; 16S rRNA uridine-516 pseudouridylate synthase and related Pseudouridylate synthase K06183; COG: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Psort location: Cytoplasmic, score: 8.87; Belongs to the pseudouridine synthase RsuA family.
       0.795
EDS08151.1
Putative radical SAM protein YgiQ; KEGG: fnu:FN0734 4.3e-131 Fe-S oxidoreductase; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87.
  
    0.795
yniC
HAD hydrolase, family IA, variant 3; KEGG: cch:Cag_0071 3.5e-19 beta-phosphoglucomutase hydrolase K01838; COG: COG0637 Predicted phosphatase/phosphohexomutase; Psort location: Cytoplasmic, score: 8.87.
  
    0.781
LytH_2
Peptidase, M23 family; KEGG: sam:MW0252 2.6e-07 lytM; peptidoglycan hydrolase K08259; COG: COG0739 Membrane proteins related to metalloendopeptidases; Psort location: Cytoplasmic, score: 8.87.
  
    0.763
rluC
Pseudouridine synthase, RluA family; KEGG: cpe:CPE1204 1.3e-51 ribosomal large subunit pseudouridine synthase C K06179; COG: COG0564 Pseudouridylate synthases, 23S RNA-specific; Psort location: Cytoplasmic, score: 8.87; Belongs to the pseudouridine synthase RluA family.
       0.727
SrfAA
AMP-binding enzyme; KEGG: ava:Ava_1613 5.8e-204 non-ribosomal peptide synthase K00644; COG: COG1020 Non-ribosomal peptide synthetase modules and related proteins; Psort location: Cytoplasmic, score: 9.96; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.707
EDS08153.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 7.80.
       0.704
recU
Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family.
       0.667
pepD
Xaa-His dipeptidase; KEGG: cpf:CPF_2512 1.2e-110 pepD; aminoacyl-histidine dipeptidase K01270; COG: COG2195 Di- and tripeptidases; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.618
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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