close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS08170.1Amidohydrolase family protein; COG: COG2159 Predicted metal-dependent hydrolase of the TIM-barrel fold; Psort location: Cytoplasmic, score: 8.87. (262 aa)    
Predicted Functional Partners:
guaB_2
CBS domain protein; KEGG: mka:MK1600 5.0e-08 guaB; IMP dehydrogenase K00088; COG: COG0517 FOG: CBS domain; Psort location: Cytoplasmic, score: 8.87.
       0.782
YicL_2
Putative membrane protein; KEGG: pae:PA1977 7.9e-05 sensor protein GLPS; COG: COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Psort location: CytoplasmicMembrane, score: 9.99.
       0.762
yclM
Amino acid kinase family; KEGG: ctc:CTC02356 1.2e-128 aspartate kinase K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score: 8.87; Belongs to the aspartokinase family.
       0.719
rplU
Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
       0.516
ntpC
KEGG: ctc:CTC00997 2.3e-29 V-type sodium ATP synthase subunit C K02119; COG: COG1527 Archaeal/vacuolar-type H+-ATPase subunit C; Psort location: Cytoplasmic, score: 8.87.
  
     0.504
rpmA
COG: COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
       0.494
EDS08173.1
COG: COG2868 Predicted ribosomal protein; Psort location: Cytoplasmic, score: 8.87.
       0.493
YbaK
YbaK/EbsC protein; COG: COG2606 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
       0.431
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: medium (62%) [HD]