Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SrrA_4KEGG: eci:UTI89_C2354 7.9e-29 baeR; transcriptional response regulatory protein BaeR K07664; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98. (214 aa)    
Predicted Functional Partners:
cssS_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: spr:spr0529 4.9e-31 vncS; VncS, histidine kinase; COG: COG0642 Signal transduction histidine kinase.
 
   0.951
EDS08189.1
Hypothetical protein.
       0.773
walR_6
Response regulator receiver domain protein; KEGG: eci:UTI89_C4496 1.2e-14 cpxR; transcriptional regulatory protein CpxR K07662; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
     0.764
walR_7
Transcriptional regulatory protein, C-terminal domain protein; KEGG: ava:Ava_3369 8.5e-16 two component transcriptional regulator, winged helix family; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
  
     0.733
cckA
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ret:RHE_CH02326 3.0e-25 probable two-component sensor histidine kinase/response regulator hybrid protein; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 0.697
thiQ
KEGG: bur:Bcep18194_A3518 4.1e-23 ABC transporter, ATPase subunit K01990; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
    0.688
phoR_5
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bca:BCE_2750 8.8e-69 histidine kinase, putative; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
 
   0.678
zraS_2
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ecp:ECP_4216 4.8e-30 sensor protein ZraS K07709; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
  
   0.644
zraS_1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: eco:b2219 1.7e-25 atoS; sensor protein AtoS for response regulator AtoC K07710; COG: COG2202 FOG: PAS/PAC domain; Psort location: CytoplasmicMembrane, score: 9.49.
  
   0.631
ResE_9
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: bcz:BCZK1343 5.4e-53 sensor histidine kinase; COG: COG0642 Signal transduction histidine kinase; Psort location: Cytoplasmic, score: 9.36.
 
 
 0.617
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (38%) [HD]