Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
lspASignal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (169 aa)    
Predicted Functional Partners:
EDS07412.1
Hypothetical protein.
     
  0.900
lspA_1
Hypothetical protein; This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
     
  0.900
rluD_3
Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
  
    0.877
EDS08193.1
S4 domain protein; KEGG: ama:AM825 0.0049 sfhB; sfhb-like protein K06180; COG: COG2302 Uncharacterized conserved protein, contains S4-like domain; Psort location: Cytoplasmic, score: 8.87.
       0.819
sepF
Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
       0.819
EDS08195.1
Pyridoxal phosphate enzyme, YggS family; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
       0.766
EDS08196.1
Hypothetical protein.
     
 0.740
EDS08198.1
Radical SAM protein, TIGR01212 family; KEGG: btk:BT9727_4481 4.7e-38 conserved hypothetical protein, possible Fe-S oxidoreductase; COG: COG1242 Predicted Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87.
       0.617
Cmk_5
Hypothetical protein; KEGG: sat:SYN_01231 2.0e-30 cytidylate kinase K00945; COG: NOG14451 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
       0.596
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
  
  
 0.581
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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