Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mrdBCell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772 Bacterial cell division membrane protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family. (374 aa)    
Predicted Functional Partners:
MrdA
Penicillin-binding protein, transpeptidase domain protein; KEGG: ppd:Ppro_2545 4.2e-57 peptidoglycan glycosyltransferase K05364; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 0.951
mreB_1
Cell shape determining protein, MreB/Mrl family; KEGG: hpa:HPAG1_1318 3.3e-37 rod shape-determining protein K01529; COG: COG1077 Actin-like ATPase involved in cell morphogenesis; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.922
pbpA
Penicillin-binding protein, transpeptidase domain protein; KEGG: mta:Moth_0911 8.7e-62 peptidoglycan glycosyltransferase K05364; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score: 9.82.
 
 0.882
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
  
 0.870
spoVD_2
Penicillin-binding protein, transpeptidase domain protein; KEGG: cac:CAC0329 1.6e-76 spoVD; sporulation specific penicillin-binding protein K03587; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score: 9.49.
 
 0.869
divIB
Hypothetical protein; COG: COG1589 Cell division septal protein; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.869
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
 
  
 0.837
spoVD_1
Penicillin-binding protein, transpeptidase domain protein; KEGG: tte:TTE1916 3.0e-91 ftsI4; Cell division protein FtsI/penicillin-binding protein 2 K03587; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score: 9.70.
 
 0.824
mraY
phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.822
mreD
Rod shape-determining protein MreD; COG: NOG16883 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
  
 0.810
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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