Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mreDRod shape-determining protein MreD; COG: NOG16883 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99. (172 aa)    
Predicted Functional Partners:
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.993
minC
Putative septum site-determining protein MinC; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
 
  
 0.965
MrdA
Penicillin-binding protein, transpeptidase domain protein; KEGG: ppd:Ppro_2545 4.2e-57 peptidoglycan glycosyltransferase K05364; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score: 9.49.
 
  
 0.954
minD
Septum site-determining protein MinD; KEGG: eci:UTI89_C1360 7.8e-61 minD; cell division inhibitor, membrane ATPase MinD K03609; COG: COG2894 Septum formation inhibitor-activating ATPase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.911
mreB_1
Cell shape determining protein, MreB/Mrl family; KEGG: hpa:HPAG1_1318 3.3e-37 rod shape-determining protein K01529; COG: COG1077 Actin-like ATPase involved in cell morphogenesis; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.899
EDS08209.1
COG: COG2003 DNA repair proteins; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0758 family.
  
  
 0.839
mrdB
Cell cycle protein, FtsW/RodA/SpoVE family; COG: COG0772 Bacterial cell division membrane protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
 
  
 0.810
EDS08196.1
Hypothetical protein.
 
     0.756
EDS06654.1
KEGG: cyb:CYB_1515 0.0081 tetratricopeptide repeat/protein kinase domain protein K08884; COG: COG0457 FOG: TPR repeat.
 
     0.752
EDS07102.1
Hypothetical protein; COG: NOG17868 non supervised orthologous group.
  
     0.746
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.