STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS08211.1Hypothetical protein; KEGG: gox:GOX1630 3.6e-63 putative oxidoreductase K00100; COG: COG2509 Uncharacterized FAD-dependent dehydrogenases; Psort location: Cytoplasmic, score: 8.87. (552 aa)    
Predicted Functional Partners:
baiN
Flavoprotein family protein; Involved in the secondary bile acid metabolism. Catalyzes two subsequent reductions of the double bonds within the bile acid A/B rings of 3-oxochol-4,6-dien-24-oyl-CoA and 12alpha-hydroxy-3-oxochol- 4,6-dien-24-oyl-CoA to yield 3-oxocholan-24-oyl-CoA and 12alpha- hydroxy-3-oxocholan-24-oyl-CoA, respectively.
 
   
 0.884
megL
Aluminum resistance protein; KEGG: ava:Ava_4213 1.1e-100 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme K01758; COG: COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance; Psort location: Cytoplasmic, score: 8.87.
       0.706
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.685
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.684
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
       0.684
EDS08210.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.75.
       0.560
EDS08214.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.552
EDS08209.1
COG: COG2003 DNA repair proteins; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0758 family.
       0.547
MrdA
Penicillin-binding protein, transpeptidase domain protein; KEGG: ppd:Ppro_2545 4.2e-57 peptidoglycan glycosyltransferase K05364; COG: COG0768 Cell division protein FtsI/penicillin-binding protein 2; Psort location: CytoplasmicMembrane, score: 9.49.
  
    0.540
mreD
Rod shape-determining protein MreD; COG: NOG16883 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
       0.535
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.