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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
baiNFlavoprotein family protein; Involved in the secondary bile acid metabolism. Catalyzes two subsequent reductions of the double bonds within the bile acid A/B rings of 3-oxochol-4,6-dien-24-oyl-CoA and 12alpha-hydroxy-3-oxochol- 4,6-dien-24-oyl-CoA to yield 3-oxocholan-24-oyl-CoA and 12alpha- hydroxy-3-oxocholan-24-oyl-CoA, respectively. (409 aa)    
Predicted Functional Partners:
EDS08211.1
Hypothetical protein; KEGG: gox:GOX1630 3.6e-63 putative oxidoreductase K00100; COG: COG2509 Uncharacterized FAD-dependent dehydrogenases; Psort location: Cytoplasmic, score: 8.87.
 
   
 0.884
megL
Aluminum resistance protein; KEGG: ava:Ava_4213 1.1e-100 Cys/Met metabolism pyridoxal-phosphate-dependent enzyme K01758; COG: COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance; Psort location: Cytoplasmic, score: 8.87.
       0.794
miaA
tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family.
       0.765
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.765
mutL
DNA mismatch repair domain protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
       0.764
EDS08214.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.669
baiF
Bile acid-CoA hydrolase; KEGG: ecs:ECs0041 1.2e-66 crotonobetainyl-CoA:carnitine CoA-transferase K08298; COG: COG1804 Predicted acyl-CoA transferases/carnitine dehydratase; Psort location: Cytoplasmic, score: 9.98; Belongs to the CoA-transferase III family.
   
  
 0.504
baiA
Bile acid 7-dehydroxylase 1/3; KEGG: cpr:CPR_0991 9.5e-56 7-alpha-hydroxysteroid dehydrogenase K00076; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score: 9.98; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.501
baiA-2
Bile acid 7-dehydroxylase 1/3; KEGG: cpr:CPR_0991 9.8e-54 7-alpha-hydroxysteroid dehydrogenase K00076; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score: 9.98; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
     
 0.501
agcS-2
Amino acid carrier protein; KEGG: hpa:HPAG1_0925 3.9e-98 D-alanine glycine permease K01613; COG: COG1115 Na+/alanine symporter; Psort location: CytoplasmicMembrane, score: 10.00.
      
 0.497
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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