Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS08221.1Toxin secretion/phage lysis holin; Psort location: CytoplasmicMembrane, score: 7.80. (172 aa)    
Predicted Functional Partners:
lytG
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; KEGG: cno:NT01CX_2157 9.9e-26 N-acetylmuramoyl-L-alanine amidase CwlL precursor (cellwall hydrolase) (autolysin) K01446; COG: COG1705 Muramidase (flagellum-specific); Psort location: Extracellular, score: 9.55.
       0.793
ltrA_3
Reverse transcriptase (RNA-dependent DNA polymerase); KEGG: rba:RB818 3.0e-25 reverse transcriptase/maturase K00986; COG: COG3344 Retron-type reverse transcriptase; Psort location: Cytoplasmic, score: 8.87.
       0.774
miaB
tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
       0.463
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (22%) [HD]