Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
clpP-2KEGG: lsl:LSL_0785 5.6e-35 clpP; ATP-dependent Clp protease proteolytic subunit K01358; COG: COG0740 Protease subunit of ATP-dependent Clp proteases; Psort location: Cytoplasmic, score: 9.65; Belongs to the peptidase S14 family. (251 aa)    
Predicted Functional Partners:
clpX-2
KEGG: bcz:BCZK4216 6.6e-96 clpX; ATP-dependent Clp protease, ATP-binding subunit K03544; COG: COG1219 ATP-dependent protease Clp, ATPase subunit; Psort location: Cytoplasmic, score: 8.87.
 
 0.891
clpX
ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
 
 0.884
clpC
ATPase family associated with various cellular activities (AAA); KEGG: sab:SAB0475 4.3e-227 clpC; endopeptidase K03696; COG: COG0542 ATPases with chaperone activity, ATP-binding subunit; Psort location: Cytoplasmic, score: 9.98; Belongs to the ClpA/ClpB family.
 
 
 0.829
EDS08239.1
Phage portal protein, HK97 family; COG: COG4695 Phage-related protein.
  
    0.819
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.797
EDS08237.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.773
EDS08236.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.697
clpP-4
ATP-dependent Clp endopeptidase, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
  
 
0.667
EDS08240.1
COG: COG4626 Phage terminase-like protein, large subunit; Psort location: Cytoplasmic, score: 8.87.
 
     0.655
clpP
KEGG: bca:BCE_0399 2.9e-54 clpP; ClpP protease family protein K01358; COG: COG0740 Protease subunit of ATP-dependent Clp proteases; Psort location: Cytoplasmic, score: 9.65; Belongs to the peptidase S14 family.
  
  
 
0.629
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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