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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIIEFtsK/SpoIIIE family protein; KEGG: reh:H16_A1582 1.5e-122 DNA segregation ATPase FtsK/SpoIIIE related protein; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score: 7.63. (796 aa)    
Predicted Functional Partners:
fhs
KEGG: chy:CHY_2385 2.7e-202 fhs; formate--tetrahydrofolate ligase K01938; COG: COG2759 Formyltetrahydrofolate synthetase; Psort location: Cytoplasmic, score: 8.87.
 
     0.809
parB
ParB-like protein; KEGG: pub:SAR11_0354 4.2e-46 parB; chromosome partitioning protein K03497; COG: COG1475 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87; Belongs to the ParB family.
  
  
 0.783
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.716
divIB
Hypothetical protein; COG: COG1589 Cell division septal protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.707
TepA
Putative endopeptidase Clp; KEGG: ctc:CTC01283 7.8e-61 ATP-dependent clp protease proteolytic subunit K01358; COG: COG0740 Protease subunit of ATP-dependent Clp proteases.
  
  
 0.704
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.679
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
   
 0.673
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
  
 0.651
ftsW_2
COG: COG0772 Bacterial cell division membrane protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
 
  
 0.635
EDS08291.1
Tetratricopeptide repeat protein; KEGG: mth:MTH977 0.00053 endo-1,4-beta-glucanase related protein K01179; COG: COG3291 FOG: PKD repeat; Psort location: Cytoplasmic, score: 8.87.
  
    0.629
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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