Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
spoIIIEFtsK/SpoIIIE family protein; KEGG: reh:H16_A1582 1.5e-122 DNA segregation ATPase FtsK/SpoIIIE related protein; COG: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; Psort location: CytoplasmicMembrane, score: 7.63. (796 aa)    
Predicted Functional Partners:
parB
ParB-like protein; KEGG: pub:SAR11_0354 4.2e-46 parB; chromosome partitioning protein K03497; COG: COG1475 Predicted transcriptional regulators; Psort location: Cytoplasmic, score: 8.87; Belongs to the ParB family.
  
  
 0.806
fhs
KEGG: chy:CHY_2385 2.7e-202 fhs; formate--tetrahydrofolate ligase K01938; COG: COG2759 Formyltetrahydrofolate synthetase; Psort location: Cytoplasmic, score: 8.87.
 
     0.794
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.752
divIB
Hypothetical protein; COG: COG1589 Cell division septal protein; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.682
TepA
Putative endopeptidase Clp; KEGG: ctc:CTC01283 7.8e-61 ATP-dependent clp protease proteolytic subunit K01358; COG: COG0740 Protease subunit of ATP-dependent Clp proteases.
  
  
 0.668
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
   
 0.667
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
  
 0.646
EDS08291.1
Tetratricopeptide repeat protein; KEGG: mth:MTH977 0.00053 endo-1,4-beta-glucanase related protein K01179; COG: COG3291 FOG: PKD repeat; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.629
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
  
  
 0.623
ftsW_2
COG: COG0772 Bacterial cell division membrane protein; Psort location: CytoplasmicMembrane, score: 10.00; Belongs to the SEDS family.
 
  
 0.619
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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