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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icdIsocitrate dehydrogenase, NADP-dependent; KEGG: tte:TTE0387 4.1e-158 icd; Isocitrate dehydrogenases K00031; COG: COG0538 Isocitrate dehydrogenases; Psort location: Cytoplasmic, score: 8.87; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (398 aa)    
Predicted Functional Partners:
DmdA_2
Aconitase domain protein; KEGG: ecp:ECP_0784 2.8e-239 aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score: 9.98.
 
 0.990
gdhA
Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; KEGG: tde:TDE0997 6.6e-119 gdhA; glutamate dehydrogenase K00261; COG: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Psort location: Cytoplasmic, score: 9.98; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.922
gdh
Glu/Leu/Phe/Val dehydrogenase, dimerization domain protein; KEGG: lsl:LSL_1297 6.0e-189 gdhA; NADP-specific glutamate dehydrogenase K00262; COG: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Psort location: Cytoplasmic, score: 9.98; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.922
PrpC2
KEGG: lla:L67186 6.4e-137 gltA; citrate synthase K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.911
gltB_1
Class II glutamine amidotransferase; KEGG: gka:GK1431 0. glutamate synthaselarge subunit K00265; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87.
    
 0.858
EDS07585.1
Aminotransferase, class I/II; KEGG: ctc:CTC01294 1.1e-118 aspartate aminotransferase K00812; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase.
  
 0.839
aspC
Aminotransferase, class I/II; KEGG: cac:CAC2832 1.8e-118 PLP-dependent aminotransferase K00811; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score: 8.87.
  
 0.839
argH
Argininosuccinate lyase; KEGG: cpe:CPE0690 2.3e-139 argH; argininosuccinate lyase K01755; COG: COG0165 Argininosuccinate lyase; Psort location: Cytoplasmic, score: 8.87.
     
 0.832
NadB
FAD binding domain protein; KEGG: fnu:FN0009 4.8e-100 L-aspartate oxidase K00278; COG: COG0029 Aspartate oxidase; Psort location: Cytoplasmic, score: 9.36.
     
 0.828
purB
Adenylosuccinate lyase; KEGG: cno:NT01CX_2118 9.8e-173 purB; adenylosuccinate lyase K01756; COG: COG0015 Adenylosuccinate lyase; Psort location: Cytoplasmic, score: 8.87.
    
 0.823
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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