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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvAKEGG: fnu:FN1411 6.2e-116 threonine dehydratase K01754; COG: COG1171 Threonine dehydratase. (404 aa)    
Predicted Functional Partners:
ilvN
KEGG: mth:MTH1443 2.6e-37 acetolactate synthase small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.962
ilvN-2
Acetolactate synthase, small subunit; KEGG: pha:PSHAb0463 1.8e-29 ilvH; acetolactate synthase isozyme III small subunit K01653; COG: COG0440 Acetolactate synthase, small (regulatory) subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.956
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.955
thrC
Threonine synthase; KEGG: cac:CAC0999 4.3e-163 thrC; threonine synthase K01733; COG: COG0498 Threonine synthase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.952
ilvB
Acetolactate synthase, large subunit, biosynthetic type; KEGG: cac:CAC3169 3.3e-165 ilvB; acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score: 8.87.
 
 0.946
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.945
ilvB-2
Acetolactate synthase, large subunit, biosynthetic type; KEGG: mac:MA3792 1.9e-153 acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score: 8.87.
 
 0.943
ltaE
Beta-eliminating lyase; KEGG: cac:CAC3420 6.2e-116 low specificity L-threonine aldolase K01620; COG: COG2008 Threonine aldolase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.933
sdaAA
KEGG: ljo:LJ1328 9.2e-58 L-serine dehydratase alpha subunit K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.923
sdaAB
KEGG: btk:BT9727_3885 1.7e-51 sdhB; L-serine dehydratase, beta subunit K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
 
 0.923
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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