| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EDS08330.1 | coaE | CLOSCI_00641 | CLOSCI_00643 | Hypothetical protein; COG: COG2848 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.702 |
| EDS08330.1 | polA | CLOSCI_00641 | CLOSCI_00644 | Hypothetical protein; COG: COG2848 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.694 |
| EDS08330.1 | yycJ | CLOSCI_00641 | CLOSCI_00642 | Hypothetical protein; COG: COG2848 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87. | Metallo-beta-lactamase domain protein; KEGG: fnu:FN0900 5.3e-39 metal dependent hydrolase; COG: COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; Psort location: Cytoplasmic, score: 8.87. | 0.735 |
| Sfp | coaE | CLOSCI_00996 | CLOSCI_00643 | Putative 4'-phosphopantetheinyl transferase sfp; KEGG: bld:BLi00407 1.8e-15 hypothetical protein K01005; COG: COG2091 Phosphopantetheinyl transferase; Psort location: Cytoplasmic, score: 8.87. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.905 |
| coaD | coaE | CLOSCI_00454 | CLOSCI_00643 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.943 |
| coaD | gmk | CLOSCI_00454 | CLOSCI_00672 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.518 |
| coaD | nadE | CLOSCI_00454 | CLOSCI_01169 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.501 |
| coaE | EDS08330.1 | CLOSCI_00643 | CLOSCI_00641 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Hypothetical protein; COG: COG2848 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87. | 0.702 |
| coaE | Sfp | CLOSCI_00643 | CLOSCI_00996 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Putative 4'-phosphopantetheinyl transferase sfp; KEGG: bld:BLi00407 1.8e-15 hypothetical protein K01005; COG: COG2091 Phosphopantetheinyl transferase; Psort location: Cytoplasmic, score: 8.87. | 0.905 |
| coaE | coaD | CLOSCI_00643 | CLOSCI_00454 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.943 |
| coaE | gmk | CLOSCI_00643 | CLOSCI_00672 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.585 |
| coaE | hemC | CLOSCI_00643 | CLOSCI_03616 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.646 |
| coaE | mgsA | CLOSCI_00643 | CLOSCI_00511 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.640 |
| coaE | mntP_1 | CLOSCI_00643 | CLOSCI_01426 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Putative sporulation protein YtaF; Probably functions as a manganese efflux pump. | 0.620 |
| coaE | nadE | CLOSCI_00643 | CLOSCI_01169 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.598 |
| coaE | polA | CLOSCI_00643 | CLOSCI_00644 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.933 |
| coaE | yycJ | CLOSCI_00643 | CLOSCI_00642 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Metallo-beta-lactamase domain protein; KEGG: fnu:FN0900 5.3e-39 metal dependent hydrolase; COG: COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; Psort location: Cytoplasmic, score: 8.87. | 0.802 |
| gmk | coaD | CLOSCI_00672 | CLOSCI_00454 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.518 |
| gmk | coaE | CLOSCI_00672 | CLOSCI_00643 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.585 |
| hemC | coaE | CLOSCI_03616 | CLOSCI_00643 | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.646 |