Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pykPyruvate kinase; KEGG: tte:TTE1815 1.2e-137 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87. (478 aa)    
Predicted Functional Partners:
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.986
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 0.968
pgi
KEGG: bcl:ABC2906 1.4e-164 pgi; glucose-6-phosphate isomerase K01810; COG: COG0166 Glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score: 9.98; Belongs to the GPI family.
  
 0.960
EDS07091.1
Malic enzyme, NAD binding domain protein; KEGG: tte:TTE2332 9.9e-125 sfcA; malic enzyme K00027; COG: COG0281 Malic enzyme; Psort location: CytoplasmicMembrane, score: 9.97.
  
 0.933
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.929
EDS04956.1
Hypothetical protein; KEGG: lac:LBA0466 8.7e-133 phosphoenolpyruvate carboxykinase (ATP) K01610; COG: COG1866 Phosphoenolpyruvate carboxykinase (ATP).
    
 0.923
pgk
Phosphoglycerate kinase; KEGG: ctc:CTC00379 9.1e-154 pgk; phosphoglycerate kinase K00927; COG: COG0126 3-phosphoglycerate kinase; Psort location: Cytoplasmic, score: 9.98.
 
 
 0.919
etfA-3
Electron transfer flavoprotein FAD-binding domain protein; KEGG: ctc:CTC01387 7.1e-16 acyl-coA dehydrogenase K00248; COG: COG1145 Ferredoxin; Psort location: Cytoplasmic, score: 8.87.
  
 0.919
EDS07543.1
KEGG: tte:TTE1208 6.1e-148 pycA; Pyruvate carboxylase, C-terminal domain/subunit K01960; COG: COG5016 Pyruvate/oxaloacetate carboxyltransferase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.915
pflB
KEGG: bce:BC0491 6.8e-268 formate acetyltransferase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score: 9.98.
   
 
 0.913
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.