close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS08339.1Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.99. (285 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; KEGG: tte:TTE1815 1.2e-137 pykF; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87.
       0.775
EDS08340.1
Hypothetical protein.
       0.639
hadI
Putative CoA-substrate-specific enzyme activase; KEGG: eci:UTI89_C5044 1.6e-18 yjiL; hypothetical protein YjiL K04111; COG: COG3580 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87.
       0.625
cdaR
Hypothetical protein; KEGG: shn:Shewana3_2682 0.00084 transcriptional regulator, CdaR K01694; COG: COG3835 Sugar diacid utilization regulator; Psort location: Cytoplasmic, score: 8.87.
  
     0.600
EDS05745.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.75.
  
     0.568
EDS08274.1
KEGG: bha:BH1417 3.6e-24 5-formyltetrahydrofolate cyclo-ligase K01934; COG: COG0212 5-formyltetrahydrofolate cyclo-ligase; Psort location: Cytoplasmic, score: 8.87.
  
    0.546
EDS07942.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
  
     0.541
PucR_2
Hypothetical protein; KEGG: shn:Shewana3_2682 0.00082 transcriptional regulator, CdaR K01694; COG: COG3835 Sugar diacid utilization regulator; Psort location: Cytoplasmic, score: 8.87.
  
     0.522
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
   
 0.502
EDS04936.1
Hypothetical protein.
  
     0.471
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.