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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS08345.1Lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; COG: NOG17940 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99. (254 aa)    
Predicted Functional Partners:
EDS08344.1
Lantibiotic protection ABC transporter permease subunit, MutG family; COG: NOG31276 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
   
 0.967
CreC
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: ctc:CTC00629 1.2e-71 spaK; subtilin biosynthesis sensor protein SpaK; COG: COG0642 Signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 9.49.
 
   
 0.959
yxlF_8
Lantibiotic protection ABC transporter, ATP-binding subunit; KEGG: fal:FRAAL1877 3.1e-41 putative ABC transporter ATP-binding protein; COG: COG1131 ABC-type multidrug transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
 
  
 0.954
PhoP_5
Response regulator receiver domain protein; KEGG: rha:RHA1_ro04741 2.5e-32 phoP; response regulator, two-component system K02483; COG: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; Psort location: Cytoplasmic, score: 9.98.
 
     0.904
EDS08761.1
ABC-2 type transporter; COG: COG0842 ABC-type multidrug transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.579
EDS06545.1
Hypothetical protein; COG: NOG17660 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87.
  
     0.513
EDS04974.1
KEGG: pen:PSEEN3665 0.00049 efflux ABC transporter, ATP-binding/permease protein; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 9.99.
  
     0.511
EDS05313.1
Efflux ABC transporter, permease protein; COG: COG0577 ABC-type antimicrobial peptide transport system, permease component; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.486
artM
KEGG: lin:lin0841 5.9e-95 similar to amino acid ABC transporter, ATP-binding protein K02028; COG: COG1126 ABC-type polar amino acid transport system, ATPase component; Psort location: CytoplasmicMembrane, score: 9.49.
       0.472
tcyB_2
KEGG: hpa:HPAG1_0922 4.8e-29 amino acid ABC transporter, permease protein; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: CytoplasmicMembrane, score: 10.00.
       0.472
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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