close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDS08361.1TIGR00255 family protein; KEGG: sab:SAB1204 0.0040 exonuclease K03546; COG: COG1561 Uncharacterized stress-induced protein; Psort location: Cytoplasmic, score: 8.87. (293 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
  
 0.905
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.842
cinA_2
Competence/damage-inducible domain protein CinA; KEGG: hsa:80308 5.5e-07 FLAD1; FAD1 flavin adenine dinucleotide synthetase homolog (S. cerevisiae) K00953; COG: COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; Psort location: Cytoplasmic, score: 8.87; Belongs to the CinA family.
 
     0.681
FbpA
COG: COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP; Psort location: Cytoplasmic, score: 8.87.
       0.668
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; KEGG: tte:TTE1376 7.5e-40 pgsA2; Phosphatidylglycerophosphate synthase K00995; COG: COG0558 Phosphatidylglycerophosphate synthase; Psort location: CytoplasmicMembrane, score: 9.99; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.620
rimO
Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily.
       0.620
coaD
Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
  
    0.563
gmk_1
Hypothetical protein; KEGG: tws:TW406 1.8e-09 gmk; guanylate kinase K00942; COG: COG0194 Guanylate kinase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.552
EDS08354.1
Hypothetical protein; Psort location: Cytoplasmic, score: 8.87.
       0.457
EDS08355.1
Acetyltransferase, GNAT family; KEGG: fnu:FN1295 1.1e-12 acetyltransferase K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score: 8.87.
       0.457
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (36%) [HD]