Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EDS08365.1Hypothetical protein; COG: COG2607 Predicted ATPase (AAA+ superfamily); Psort location: Cytoplasmic, score: 8.87. (429 aa)    
Predicted Functional Partners:
pheA
KEGG: mgm:Mmc1_1881 1.4e-45 prephenate dehydratase K01713; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score: 9.98.
       0.818
EDS08367.1
Hypothetical protein; KEGG: smu:SMU.1291c 0.00011 putative chorismate mutase K04516; Psort location: Cytoplasmic, score: 8.87.
       0.757
EDS08368.1
Hypothetical protein; COG: NOG08169 non supervised orthologous group.
 
     0.600
EDS08369.1
Nitroreductase family protein; KEGG: mma:MM1584 2.6e-14 NADPH-flavin oxidoreductase; COG: COG0778 Nitroreductase; Psort location: Cytoplasmic, score: 8.87.
       0.485
pyrB
KEGG: cac:CAC2654 6.3e-107 aspartate carbamoyltransferase catalytic subunit K00609; COG: COG0540 Aspartate carbamoyltransferase, catalytic chain; Psort location: Cytoplasmic, score: 9.98; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
       0.450
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
   0.433
pyrI
Aspartate carbamoyltransferase regulatory chain, allosteric domain protein; KEGG: ctc:CTC02383 6.4e-34 aspartate carbamoyltransferase regulatory chain K00610; COG: COG1781 Aspartate carbamoyltransferase, regulatory subunit; Psort location: Cytoplasmic, score: 8.87.
       0.427
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.