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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ydiMCOG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score: 10.00. (425 aa)    
Predicted Functional Partners:
aroE
Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
    0.909
iolI
AP endonuclease, family 2; KEGG: atc:AGR_L_678 0.00028 4-hydroxyphenylpyruvate dioxygenase K00457; COG: COG1082 Sugar phosphate isomerases/epimerases; Psort location: Cytoplasmic, score: 8.87.
 
    0.840
gltC_4
LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 2.6e-21 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family.
 
    0.808
aroD
3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
 
     0.741
EDS08382.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: afu:AF1262 6.3e-107 noxB-2; NADH oxidase (NoxB-2) K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 8.87.
 
    0.723
EDS08737.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: lwe:lwe0460 8.9e-195 NADH:flavin oxidoreductase K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 8.87.
 
    0.630
EDS08379.1
Hypothetical protein; COG: NOG07813 non supervised orthologous group; Psort location: CytoplasmicMembrane, score: 9.99.
 
     0.609
gltC_5
LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 1.6e-21 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family.
  
    0.602
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 
 
 0.586
EDS05303.1
Chorismate mutase; KEGG: stc:str1181 3.6e-08 aroH; chorismate mutase K04516; COG: COG1605 Chorismate mutase; Psort location: Cytoplasmic, score: 8.87.
 
 
 
 0.507
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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