Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EDS08382.1Pyridine nucleotide-disulfide oxidoreductase; KEGG: afu:AF1262 6.3e-107 noxB-2; NADH oxidase (NoxB-2) K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 8.87. (641 aa)    
Predicted Functional Partners:
aroE
Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
  
 0.813
urdA
FAD binding domain protein; KEGG: ctc:CTC01488 1.6e-55 fumarate reductase flavoprotein subunit K00244; COG: COG3976 Uncharacterized protein conserved in bacteria; Psort location: CytoplasmicMembrane, score: 9.49.
 
 
 0.726
ydiM
COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score: 10.00.
 
   
 0.724
iolI
AP endonuclease, family 2; KEGG: atc:AGR_L_678 0.00028 4-hydroxyphenylpyruvate dioxygenase K00457; COG: COG1082 Sugar phosphate isomerases/epimerases; Psort location: Cytoplasmic, score: 8.87.
 
     0.702
carD_2
COG: COG2086 Electron transfer flavoprotein, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.692
EtfB
COG: COG2086 Electron transfer flavoprotein, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.692
carD_1
COG: COG2086 Electron transfer flavoprotein, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.692
nifJ
Pyruvate synthase; KEGG: cno:NT01CX_1854 0. nifJ; pyruvate:ferredoxin (flavodoxin) oxidoreductase K00168; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.678
etfA-3
Electron transfer flavoprotein FAD-binding domain protein; KEGG: ctc:CTC01387 7.1e-16 acyl-coA dehydrogenase K00248; COG: COG1145 Ferredoxin; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.677
gltC_4
LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 2.6e-21 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family.
 
   
 0.646
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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