Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
iolIAP endonuclease, family 2; KEGG: atc:AGR_L_678 0.00028 4-hydroxyphenylpyruvate dioxygenase K00457; COG: COG1082 Sugar phosphate isomerases/epimerases; Psort location: Cytoplasmic, score: 8.87. (279 aa)    
Predicted Functional Partners:
aroE
Putative shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
  
 0.858
ydiM
COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score: 10.00.
 
    0.843
gltC_4
LysR substrate binding domain protein; KEGG: shn:Shewana3_3435 2.6e-21 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score: 9.98; Belongs to the LysR transcriptional regulatory family.
 
     0.822
EDS08384.1
Hypothetical protein; Psort location: Extracellular, score: 8.82.
       0.773
EDS08382.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: afu:AF1262 6.3e-107 noxB-2; NADH oxidase (NoxB-2) K00359; COG: COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Psort location: Cytoplasmic, score: 8.87.
 
     0.702
EDS08647.1
Phage tail tape measure protein, TP901 family; KEGG: eci:UTI89_C5128 0.0022 putative tail length tape measure protein precursor K00924; COG: COG5280 Phage-related minor tail protein.
  
     0.478
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
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