Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prsRibose-phosphate diphosphokinase; KEGG: cac:CAC0819 1.3e-97 phosphoribosylpyrophosphate synthetase K00948; COG: COG0462 Phosphoribosylpyrophosphate synthetase; Psort location: Cytoplasmic, score: 8.87; Belongs to the ribose-phosphate pyrophosphokinase family. (391 aa)    
Predicted Functional Partners:
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
   
 
 0.940
rbsK-3
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.930
pgcA
Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: cac:CAC2337 6.6e-167 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score: 8.87.
  
 0.921
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
  
 0.916
purF_1
KEGG: sfu:Sfum_0268 4.9e-139 amidophosphoribosyltransferase K00764; COG: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; Psort location: Cytoplasmic, score: 8.87; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
 0.916
rbsK-2
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.912
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
   
 0.912
RpiB_3
Sugar-phosphate isomerase, RpiB/LacA/LacB family; KEGG: sth:STH2337 2.7e-26 ribose 5-phosphate isomerase K01808; COG: COG0698 Ribose 5-phosphate isomerase RpiB.
  
 
 0.912
rpiB_2
Sugar-phosphate isomerase, RpiB/LacA/LacB family; KEGG: rru:Rru_A1334 9.7e-31 ribose 5-phosphate isomerase B K01819; COG: COG0698 Ribose 5-phosphate isomerase RpiB.
  
 
 0.912
rpiB
KEGG: sth:STH2337 6.2e-52 ribose 5-phosphate isomerase K01808; COG: COG0698 Ribose 5-phosphate isomerase RpiB; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.912
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.