Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (360 aa)    
Predicted Functional Partners:
pdxB
KEGG: bce:BC3248 1.2e-105 D-3-phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 0.997
pdxB-2
KEGG: hwa:HQ2066A 3.5e-58 serA; phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.65; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.965
pdxB-3
KEGG: hwa:HQ2066A 2.6e-60 serA; phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.965
pdxB-4
4-phosphoerythronate dehydrogenase; KEGG: bsu:BG13475 1.7e-74 yoaD; similar to phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score: 9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.965
thrC
Threonine synthase; KEGG: cac:CAC0999 4.3e-163 thrC; threonine synthase K01733; COG: COG0498 Threonine synthase; Psort location: Cytoplasmic, score: 8.87.
   
 0.945
cysK
Cysteine synthase A; KEGG: chy:CHY_0808 2.3e-102 cysK; cysteine synthase A K01738; COG: COG0031 Cysteine synthase; Psort location: Cytoplasmic, score: 8.87; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.913
cysK-2
Cysteine synthase A; KEGG: bld:BLi00089 7.0e-76 cysK; cysteine synthetase A; RBL03196 K01738; COG: COG0031 Cysteine synthase; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.913
pheA
KEGG: mgm:Mmc1_1881 1.4e-45 prephenate dehydratase K01713; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score: 9.98.
  
  
 0.872
EDS05303.1
Chorismate mutase; KEGG: stc:str1181 3.6e-08 aroH; chorismate mutase K04516; COG: COG1605 Chorismate mutase; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.872
ilvB
Acetolactate synthase, large subunit, biosynthetic type; KEGG: cac:CAC3169 3.3e-165 ilvB; acetolactate synthase large subunit K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score: 8.87.
  
  
 0.753
Your Current Organism:
Clostridium scindens
NCBI taxonomy Id: 411468
Other names: Clostridium scindens ATCC 35704, [. scindens ATCC 35704, [Clostridium] scindens ATCC 35704
Server load: low (10%) [HD]